Not really. It is very easy to remove the valve assembly from the kettle, disassemble it and thoroughly sanitize it leaving nothing to contaminate the wort during fermentation. I, however, don't usually bother with it and only occasionally take it apart. I use the brew in a bag method to mash, boil, and ferment in my Anvil kettle. After the boil, the wort is sterile, so I close up the kettle and let it sit overnight to cool, then aerate, pitch the yeast and seal it up. Never had any ill effects from the trub in the bottom of the kettle.